Investigating Cardiac Arrhythmia
Every heart beat is governed by an electrical impulse that spreads throughout the cardiac muscle and results in a coordinated contraction. The electrical signals can be monitored intracellularly as action potentials and extracellularly as electrocardiograms (ECG).
Cardiac arrhythmia is characterized by an irregular or abnormal heart beat, which is the central focus for DARC.
The Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC) was established in September 2005 with the aim of clarifying how specific molecular alterations in cardiac muscle cells cause electrical instability and generate arrhythmias.